Following a speech announcing plans to relaunch the White House's "Cancer Moonshot" initiative on Wednesday, President Joe Biden seemed to lose his way as he left the podium, first wandering in the wrong direction, then turning back to shake hands with several officials before apparently being reminded by Sen. Amy Klobuchar (D-Minn.) to put on his mask. Ultimately, Biden was led away from the podium with a little help from first lady Jill Biden.

What has been the response?

As always, the folks on Twitter can be counted on to call out the president's failings. First, Biden did that creepy whisper thing again. Why doesn't anyone tell him to stop doing that?

WHAT is this creep talking about?pic.twitter.com/UIH6LfmNVK

— Danny De Urbina (@Danny De Urbina) 1643830544

After he finished his thrilling speech, the president wandered away from the podium, in the wrong direction, then turned back to to do a bit of maskless handshaking before being reminded by Sen. Klobuchar to put his mask on.

Joe Brandon forgets his mask, roams around the White House\u2014 breathing on people and shaking their hands.\n\nSen. Klobuchar is caught on camera seemingly reminding him.\n\nWATCH.pic.twitter.com/FUmJMMxwr3

— Benny (@Benny) 1643831168

Finally, the first lady came to the rescue and led him off the stage, holding his hand as he shuffled and appeared to be on the verge of losing his balance. "So much strength communicated here," a video posted on Twitter was captioned.

So much strength being communicated here...pic.twitter.com/yfY5dCuEcm

— Danny De Urbina (@Danny De Urbina) 1643831293

The replies on Twitter were less-than-favorable:

Putin is raising the white flag after this display of power.pic.twitter.com/OlU80PQAhJ

— Unicorn Spit (@Unicorn Spit) 1643836311

WTF man. This is the leader of the free world, lovely.

— The Girl That Wasn\u2019t There (@The Girl That Wasn\u2019t There) 1643835047

This is honestly what is doing the most damage to this regime. If they won't even be honest about something so utterly blatant, then how can you trust them about anything else

— George Floyd's Half-Eaten Speedball (@George Floyd's Half-Eaten Speedball) 1643833162

Looks like at least one person attempted to come to the president's defense with what another Twitter user called an "unnecessary Trump reference."

pic.twitter.com/ujgUJ2SoGZ

— Brian Brewer (@Brian Brewer) 1643839862