Joe Rogan weighed in on the ongoing saga between Johnny Depp and Amber Heard. The prolific podcaster proclaimed that Heard is "full of s**t" and the defamation trial is a "big win" for Depp. Rogan also slammed Disney for booting Depp as the star of "Pirates of the Caribbean."

During Tuesday's episode of "The Joe Rogan Experience," the podcast host discussed the $50 million defamation trial with fellow comedian Jessica Kirson.

"I'm watching this trial, and, like, it's a cautionary tale about believing in bulls**t, forming a narrative in your head like, 'We’re rebels together,'" Rogan told Kirson.

"That’s what I felt like about Anthony Bourdain and his relationship to that crazy woman," Rogan said, in an apparent reference to Italian actress Asia Argento.

"You're seeing it all play out in court," he added. "Like you're seeing all the crazy come out."

The two comedians joked about Depp's claim that Heard deposited a "fecal delivery" in their bed.

Rogan commented on the claim by Heard's attorneys that the 36-year-old "Aquaman" actress used makeup from Milani Cosmetics to hide bruises that were allegedly caused by domestic violence actions by Depp. However, the specific makeup was reportedly released in December 2017, and Heard filed for divorce from Depp in May 2016.

"She said that she used specific makeup to cover all of her bruises that Johnny gave her – which is not true," Rogan stated. "Well, the problem is it was a specific makeup. It turns out that the company didn't even make that makeup at the time that she was claiming she was using it."

"But that's what happens with people like that," Rogan continued. "People that are just completely manipulative and full of s**t like them."

Rogan referenced an article written by stand-up comedian Doug Stanhope – who is a friend of Depp.

Guest-writing for the Wrap, Stanhope asserted that Depp "was pilloried in the press for domestic violence" and that Heard would "manipulate and f*** with him for years."

"Johnny Depp got used, manipulated, set up and made to look like an a**hole. And he saw it coming and didn’t or couldn’t do anything to stop it," Stanhope wrote.

The UFC commentator said Stanhope told him that Heard is "out of her f***ing mind" and agreed with Rogan that she is "like a crazy actress."

Kirson added, "Of course, there's a ton of them."

Rogan also noted that Depp has been using drugs for a long time.

"He was famous when he was 20," Rogan said of the A-list actor. "And I don't think you get any kind of perspective like that. I think you're f***ed."

Depp has admitted to first experimenting with drugs at age 11.

Rogan said the defamation trial "is a big win for Johnny Depp," but a "big loss for 'Pirates of the Caribbean.'"

Rogan then bashed Disney, "How about f*** you guys. You got rid of the best f***ing pirate you’ve ever had for a crazy lady. You f***ed up."

Two or three days after the Washington Post published Heard's December 2018 op-ed about being a victim of domestic violence, Depp said that Disney informed him that the company would not cast him again as Captain Jack Sparrow in the successful "Pirates of the Caribbean" franchise.

"And also having worked on those films with those people, and having put a lot of my own rewriting, dialogue, scenes, and jokes and whatever they are," Depp said in court on Monday. "I didn't quite understand how, after that long relationship, and quite a successful relationship, certainly for Disney, that suddenly I was guilty until proven innocent."

Depp is suing Heard for $50 million because of the Washington Post op-ed piece, claiming that the article caused him to be blacklisted from Hollywood. Heard is countersuing her ex-husband for $100 million in damages – claiming that Depp's legal team made false claims about her accusations.

The trial is in its third week and is expected to last six weeks.

(WARNING: Explicit language)

The Johnny Depp-Amber Heard Trial www.youtube.com