Horowitz: New study shows more effective immunity from prior infection than in vaccinated among organ transplant recipients



Few people are as immunocompromised and vulnerable to COVID as solid organ transplant recipients (SOTRs). Those are the people whom the medical establishment suggests should get shots and boosters early and often — even if they have to "mix and match" different variations of the shots. However, given the fact that these people are also the most vulnerable to complications from the pathogenic spike protein of the shots, why are doctors not first making sure they don't have natural immunity? A new study demonstrates that it is criminal to assume the risks of vaccination for SOTRs with prior infection.

We already have at least 122 studies attesting to the durability of immunity from prior SARS-CoV-2 infection, many of which clearly show that immunity to be much stronger and longer-lasting than vaccine-mediated immunity. However, a new study from researchers at Ajmera Transplant Centre, University Health Network, in Toronto, Canada, demonstrates that even organ transplant patients have robust T cell immunity from prior infection, much greater than those who are vaccinated.

"Vaccinated SOTRs mounted significantly lower proportions of S-specific polyfunctional CD4 + T-cells after two doses, relative to unvaccinated SOTRs with prior COVID-19," concluded the authors of the study, published in the Journal of Infectious Diseases. "Together, these results suggest that SOTR generate robust T-cell responses following natural infection that correlate with disease severity but generate comparatively lower T-cell responses following mRNA vaccination."

Rather than studying the less meaningful antibody responses, the researchers studied T cell responses in three cohorts at Toronto's University Health Network (UHN) Transplant Centre: SOTRs who had prior infection but were not subsequently vaccinated, SOTRs who were vaccinated 4-6 weeks prior to the study but never had the virus, and a control group of regular non-SOTRs with prior COVID. While the non-immunocompromised naturally immune cohort obviously mounted the greatest T cell response, the study still found that SOTRs with prior immunity had robust antigen-specific helper (CD4) and killer (CD8) T cells. Overall, the researchers found a detectable antigen-specific T-cell response in SOTRs with prior immunity at a 41.4% greater frequency than in the vaccine-only group. Also, most of those in the vaccine cohort received the Moderna shot, which is believed to be more potent than the Pfizer shot.

The findings of this study are a bombshell, because they suggest, at least in the short run, that even the most immunocompromised people with prior infection mount a serious antigen-specific T cell response that, unlike the vaccines, targets the nucleocapsid and membrane of the virus, not just the spike protein. While there is no long-term follow up in this study of SOTRs, it is important to remember that there are endless studies showing long-term and likely lifetime immunity from prior infection in the general healthy population. At the same time, we already have numerous studies and the reality of the current hard data from fully vaccinated countries hit hard with a new spread that the vaccine-mediated immunity completely wears off even for healthy people after six months.

Moreover, studies have already shown that the immunity conveyed by the shots might be particularly short-lived for the immunocompromised. For example, a study from Puerto Rico's Department of Health recently found the shots to be 0% effective in those 85 years and older after 150-200 days after vaccination. A massive Swedish study of half the country's population showed "notable waning among men, older frail individuals, and individuals with comorbidities" after about six months.

The results of the SOTR study raise some serious questions:

  1. How can our government continue to ignore the power of natural immunity if it is this potent even in organ transplant recipients?
  2. How can we continue denying organ transplants to those who don't get the shot when some of them already had the virus and the shot itself doesn't work much?
  3. What is our solution to the immunocompromised? The shots barely work and will likely not work at all with the new variants, yet they are most dangerous to those people. They have never even been tested in people with kidney failure, much less an organ transplant. Are they supposed to live in their homes forever and atrophy with no safe and effective solution? Why is the government not studying the idea of using preventives like ivermectin, nitazoxanide, or monoclonal antibodies? A recent study of the general population showed that Regeneron given pre-emptively could work for at least eight months of protection without any of the severe risks that are associated with the failed shots. Our government won't even advise these people to use Betadine nasal spray after being around people.

Just how vociferously is our government working to deny natural immunity? At the other end of the health spectrum from elderly transplant patients are healthy children. As scandalous as it is to risk the shot on healthy kids, it's unfathomable to push the shot on kids who also had prior infection. Already in March, the government estimated that 42% of children 5-17 had prior infection, and that was long before the "Delta wave," which was more transmissible and seemed to infect kids more than the ancestral strain. We all assumed that a solid majority would have been infected by now and were waiting for new data to be published. But finally the CDC has updated its numbers, and you will never guess the new data. Immunity magically slid backward!

CDC finally updated their burden estimates... and they bizarrely find that the percent of age 0 to 17 ever-infected fell from 36.7% through May to just 29.9% through September.\n\nEven more bizarre: they claim a higher % of symptomatic COVID than infection. Literally impossible.pic.twitter.com/B3ujqf5Csw

— Phil Kerpen (@kerpen) 1636496130

Although they don't have new numbers isolated for 5- to 17-year-olds (excluding really young kids and babies who were generally more isolated), their numbers for the 0-17 cohort have slid backward from 36.7% through May to just 29.9% through September ... after Delta! This makes no sense because the media and our government were panicking about this wave hitting the schools much harder. For those with children in schools, we can attest to that fact that last year barely any kids got the virus, whereas this year more seemed to get it (although still mildly) and, unlike before, even spread it in the classrooms to some degree. There is simply no way that a majority of children are not already immune.

This is yet another example of the government retracting a talking point, data point, or study once our side begins using it.

What will it take for people to wake up and realize we are being lied to?

Johns Hopkins physician criticizes ‘backwards’ vaccine mandates, pushes natural immunity



Dr. Marty Makary of Johns Hopkins University School of Medicine says blanket COVID-19 vaccine mandates are ruining people's lives, and says that natural immunity against the coronavirus is far more effective than vaccinated immunity.

What are the details?

Makary, who is editor-in-chief of MedPage Today, told The Daily Wire's "Morning Wire" on Thursday that studies have shown natural immunity against the coronavirus has shown to be 27 times more effective than vaccinated immunity.

“The data on natural immunity are now overwhelming," Makary insisted. “It turns out the hypothesis that our public health leaders had that vaccinated immunity is better and stronger than natural immunity was wrong. They got it backwards. And now we've got data from Israel showing that natural immunity is 27 times more effective than vaccinated immunity. And that supports 15 other studies."

Makary added that blanket mandates are ruining people's lives in that they are losing jobs for refusing the jabs.

"It's ruining the lives of people who are getting fired," he continued. "Nurses, who are heroes, are now getting laid off. Soldiers are getting dishonorably discharged. ... They've got immunity. It's just not the type that our public health officials have sanctioned."

Makary pointed out that this is "not a failure of science" — but a "failure of government."

"[H]ow about some flexibility?" he asked. "How about recognizing natural immunity and allowing those who have circulating antibodies to get credit? That's how they do it in parts of Europe, and that's how they do it in Israel."

Makary added that he believes immunity due to a previous coronavirus infection is helping the numbers of confirmed COVID-19 cases to decline.

"That decline is really natural immunity kicking in," he reasoned. "What we're seeing is that when a very few people in a population are susceptible, that is almost everybody has either had COVID or the vaccine. You do see this rapid decline. It's basically part of a herd immunity kicking in. ... I think we're done with the surges. What we may see is bumping cases, seasonally, depending on pockets of the country where there's low immunity rates. And remember: Breakthrough infections are real. They will happen, but they have downgraded COVID from a major public health threat to a mild, common, cold-like illness."

The outlet also pointed out that Makary stressed that vaccine-related health complications are "exceedingly rare."

"When I talked to doctors nationwide, it's pretty clear that the vaccine-related complications are exceedingly rare and the vaccines we have are safer than any other vaccine we've ever had in the past," he explained. "And I think if you if you're on the fence about getting vaccinated, you want to do it right now, like today, because we are getting to a point where it's so contagious, it's ripping through the population pretty quickly."

Horowitz: 15 studies that indicate natural immunity from prior infection is more robust than the COVID vaccines



It's the 800-poundgorilla in the pandemic. The debate over forced vaccination with an ever-waning vaccine is cresting right around the time when the debate should be moot for a lot of people. Among the most fraudulent messages of the CDC's campaign of deceit is to force the vaccine on those with prior infection, who have a greater degree of protection against all versions of the virus than those with any of the vaccines. It's time to set the record straight once and for all that natural immunity to SARS-CoV-2 is broader, more durable, and longer-lasting than any of the shots on the market today. Our policies must reflect that reality.

It should be noted that this exercise is not even necessary now that our own government concedes that immunity from the vaccines, particularly the Pfizer shot, wanes each month. With the Mayo Clinic researchers suggesting, based on old data that likely got even worse since, that Pfizer's efficacy against infection is only 42%, there is no reason to even attempt to compare this degree of immunity to the near-perfect immunity of prior infection, even against Delta. It should be obvious to any intellectually honest person that an unvaccinated individual with prior infection is exponentially safer to be around than someone who had the vaccines but not prior infection.

Remember, a significant portion of the population already got infected, and when the latest Delta wave is over in the South, the region will likely reach clear supermajorities of the population with immunity, as was found in India following the circulation of this very contagious strain of the virus.

Now consider the fact that studies have shown those with prior infection are associated with 4.4x increased odds of clinically significant side effects following mRNA vaccination. Thus, it is as scandalous as it is unnecessary to vaccinate those with prior infection, even if one supports vaccination for those without prior immunity. But as you can imagine, that would take a massive share of the market off the table from the greedy hands of Big Pharma.

To that end, it's important to clarify once and for all, based on the current academic literature, that yes, people with prior infection are indeed immune, more so than those with vaccines. Here is just a small list of some of the more recent studies, which demonstrate the effectiveness of natural immunity — even from mild infection — much later into the pandemic than the study window of the vaccines:

1) New York University, May 3, 2021

The authors studied the contrast between vaccine immunity and immunity from prior infection as it relates to stimulating the innate T-cell immunity, which is more durable than adaptive immunity through antibodies alone. They concluded, "In COVID-19 patients, immune responses were characterized by a highly augmented interferon response which was largely absent in vaccine recipients. Increased interferon signaling likely contributed to the observed dramatic upregulation of cytotoxic genes in the peripheral T cells and innate-like lymphocytes in patients but not in immunized subjects."

The study further notes: "Analysis of B and T cell receptor repertoires revealed that while the majority of clonal B and T cells in COVID-19 patients were effector cells, in vaccine recipients clonally expanded cells were primarily circulating memory cells." What this means in plain English is that effector cells trigger an innate response that is quicker and more durable, whereas memory response requires an adaptive mode that is slower to respond. Natural immunity conveys much more innate immunity, while the vaccine mainly stimulates adaptive immunity.

2) Washington University, St. Louis, Missouri, May 24, 2021, published in Nature

The media scared people last year into thinking that if antibody levels wane, it means their immunity is weakening, as we are indeed seeing with the vaccines today. But as Nature wrote, "People who recover [even] from mild COVID-19 have bone-marrow cells that can churn out antibodies for decades." Thus, aside from the robust T-cell memory that is likely lacking from most or all vaccinated individuals, prior infection creates memory B cells that "patrol the blood for reinfection, while bone marrow plasma cells (BMPCs) hide away in bones, trickling out antibodies for decades" as needed.

It's therefore not surprising that early on in the pandemic, an in-vitro study in Singapore found the immunity against SARS-CoV-2 to last even 17 years later from SARS-1-infected patients who never even had COVID-19.

3) Cleveland Clinic, June 19, 2021

In a study of 1,359 previously infected health care workers in the Cleveland Clinic system, not a single one of them was reinfected 10 months into the pandemic, despite some of these individuals being around COVID-positive patients more than the regular population.

4) Fred Hutchinson Cancer Research Center, Seattle/Emory University, Washington, July 14, 2021, published in Cell Medicine

The study found that most recovered patients produced durable antibodies, memory B cells, and durable polyfunctional CD4 and CD8 T cells, which target multiple parts of the virus. "Taken together, these results suggest that broad and effective immunity may persist long-term in recovered COVID-19 patients," concluded the authors. In other words, unlike with the vaccines, no boosters are required to assist natural immunity.

5) University of California, Irvine, July 21, 2021

The authors conclude: "Natural infection induced expansion of larger CD8 T cell clones occupied distinct clusters, likely due to the recognition of a broader set of viral epitopes presented by the virus not seen in the mRNA vaccine" (emphasis added).

6) University of California, San Francisco, May 12, 2021

Conclusion: "In infection-naïve individuals, the second dose boosted the quantity but not quality of the T cell response, while in convalescents the second dose helped neither. Spike-specific T cells from convalescent vaccinees differed strikingly from those of infection-naïve vaccinees, with phenotypic features suggesting superior long-term persistence and ability to home to the respiratory tract including the nasopharynx."

Given that we know the virus spreads through the nasopharynx, the fact that natural infection conveys much stronger mucosal immunity makes it clear that the previously infected are much safer to be around than infection-naive people with the vaccine. The fact that this study artfully couched the choices between vaccinated naive people and vaccinated recovered rather than just plain recovered doesn't change the fact that it's the prior infection, not the vaccine, conveying mucosal immunity. In fact, studies now show that infected vaccinated people contain just as much viral load in their nasopharynx as those unvaccinated, a clearly unmistakable conclusion from the virus spreading wildly in many areas with nearly every adult vaccinated.

7) Israeli researchers, August 22, 2021

Aside from more robust T cell and memory B cell immunity, which is more important than antibody levels, Israeli researchers found that antibodies wane slower among those with prior infection. "In vaccinated subjects, antibody titers decreased by up to 40% each subsequent month while in convalescents they decreased by less than 5% per month."

8) Irish researchers, published in Wiley Review, May 18, 2021

Researchers conducted a review of 11 cohort studies with over 600,000 total recovered COVID patients who were followed up with over 10 months. The key finding? Unlike the vaccine, after about four to six months, they found "no study reporting an increase in the risk of reinfection over time."

9) Cornell University, Doha, Qatar, published in the Lancet, April 27, 2021

This is one of the only studies that analyzed the population‐level risk of reinfection based on whole genome sequencing in a subset of patients with supporting evidence of reinfection. Researchers estimate the risk at 0.66 per 10,000 person-weeks. Most importantly, the study found no evidence of waning of immunity for over seven months of the follow-up period. The few reinfections that did occur "were less severe than primary infections," and "only one reinfection was severe, two were moderate, and none were critical or fatal." Also, unlike many vaccinated breakthrough infections in recent weeks that have been very symptomatic, "most reinfections were diagnosed incidentally through random or routine testing, or through contact tracing."

10) Israeli researchers, April 24, 2021

Several months ago, Israeli researchers studied 6.3 million Israelis and their COVID status and were able to confirm only one death in the entire country of someone who supposedly already had the virus, and he was over 80 years old. Contrast that to the torrent of hospitalizations and deaths we are seeing in those vaccinated more than five months ago in Israel.

11) French researchers, May 11, 2021

Researchers tested blood samples from health care workers who never had the virus but got both Pfizer shots against blood samples from those health care workers who had a previous mild infection and a third group of patients who had a serious case of COVID. They found, "No neutralization escape could be feared concerning the two variants of concern [Alpha and Beta] in both populations" of those previously infected.

12) Duke-NUS Medical School, Singapore, published in Journal of Experimental Medicine

Many people are wondering: If they got only an asymptomatic infection, are they less protected against future infection than those who suffered infection with more evident symptoms? These researchers believe the opposite is true. "Asymptomatic SARS-CoV-2–infected individuals are not characterized by weak antiviral immunity; on the contrary, they mount a highly functional virus-specific cellular immune response," wrote the authors after studying T cell responses from both symptomatic and asymptomatic convalescent patients. If anything, they found that those with asymptomatic infection only had signs of non-inflammatory cytokines, which means that the body is primed to deal with the virus without producing that dangerous inflammatory response that is killing so many hospitalized with the virus.

13) Korean researchers, published in Nature Communications on June 30, 2021

The authors found that the T cells created from convalescent patients had "stem-cell like" qualities. After studying SARS-CoV-2-specific memory T cells in recovered patients who had the virus in varying degrees of severity, the authors concluded that long-term "SARS-CoV-2-specific T cell memory is successfully maintained regardless of the severity of COVID-19."

14) Rockefeller University, July 29, 2021

The researchers note that far from suffering waning immunity, memory B cells in those with prior infection "express increasingly broad and potent antibodies that are resistant to mutations found in variants of concern." They conclude that "memory antibodies selected over time by natural infection have greater potency and breadth than antibodies elicited by vaccination." And again, this is even before getting into the innate cellular immunity which is exponentially greater in those with natural immunity.

15) Researchers from Madrid and Mount Sinai, New York, March 22, 2021

Until now, we have established that natural immunity provides better adaptive B cell and innate T cell responses that last longer and work for the variants as compared to the vaccines. Moreover, those with prior infection are at greater risk for bad side effects from the vaccines, rendering the campaign to vaccinate the previously infected both unnecessary and dangerous. But the final question is: Do the vaccines possibly harm the superior T cell immunity built up from prior infection?

Immunologists from Mount Sinai in New York and Hospital La Paz in Madrid have raised serious concerns. In a shocking discovery after monitoring a group of vaccinated people both with and without prior infection, they found "in individuals with a pre-existing immunity against SARS-CoV-2, the second vaccine dose not only fail to boost humoral immunity but determines a contraction of the spike-specific T cell response." They also note that other research has shown "the second vaccination dose appears to exert a detrimental effect in the overall magnitude of the spike-specific humoral response in COVID-19 recovered individuals."

As early as March 27, among the many accurate statements Dr. Fauci made before he became a political animal, he declared he was "really confident" in the immunity conferred by prior infection. That was long before 17 months of data and dozens of studies confirmed that. Yet, today, there are thousands of doctors and nurses with infinitely better immunity than what the vaccines can confer who are losing their jobs during a staffing crisis for not getting the shots. Just know that the big lie about natural immunity is perhaps the most verifiable lie, but it is likely not the only lie with devastating consequences we are being told about the virus, the vaccines, and alternative treatment options.