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Florida Surgeon General Dr. Joseph Ladapo is advocating a stoppage in the use of mRNA COVID-19 vaccines.
"I am calling for a halt to the use of mRNA COVID-19 vaccines," Ladapo declared in a statement on X. "The U.S. Food and Drug Administration and the Centers for Disease Control and Prevention have always played it fast and loose with COVID-19 vaccine safety, but their failure to test for DNA integration with the human genome — as their own guidelines dictate — when the vaccines are known to be contaminated with foreign DNA is intolerable."
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In a May 2023 letter to FDA Commissioner Robert Califf and then-CDC Director Rochelle Walensky, Ladapo had declared, "Your ongoing decision to ignore many of the risks associated with mRNA COVID-19 vaccines, alongside your efforts to manipulate the public into thinking they are harmless, have resulted in deep distrust in the American health care system."
Then in a December 2023 letter to Califf and CDC Director Mandy Cohen, Ladapo raised the issue of DNA fragments in the vaccines. "In addition to my previous letter, I am writing to you to address the recent discovery of host cell DNA fragments within the Pfizer and Moderna COVID-19 mRNA vaccines," Ladapo wrote.
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But in a letter of response later in December, Peter Marks, director of the FDA's Center for Biologics Evaluation and Research, said that the agency "is confident in the quality, safety, and effectiveness of the COVID-19 vaccines," and that "with over a billion doses of the mRNA vaccines administered, no safety concerns related to residual DNA have been identified." Marks wrote that "it is quite implausible that the residual small DNA fragments located in the cytosol could find their way into the nucleus through the nuclear membrane present in intact cells and then be incorporated into chromosomal DNA."
Now Ladapo is calling for a halt in mRNA COVID-19 vaccine usage.
"DNA integration poses a unique and elevated risk to human health and to the integrity of the human genome, including the risk that DNA integrated into sperm or egg gametes could be passed onto offspring of mRNA COVID-19 vaccine recipients. If the risks of DNA integration have not been assessed for mRNA COVID-19 vaccines, these vaccines are not appropriate for use in human beings," he said in a statement, according to a Florida Department of Health press release. "Providers concerned about patient health risks associated with COVID-19 should prioritize patient access to non-mRNA COVID-19 vaccines and treatment."
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FDA responds to Ladapo letter about DNA fragments detected in mRNA COVID-19 vaccines
In response to a letter in which Florida Surgeon General Joseph Ladapo noted the detection of DNA fragments in mRNA COVID-19 vaccines, Peter Marks, director of the U.S. Food and Drug Administration's Center for Biologics Evaluation and Research, emphasized the FDA's view that the shots are safe and effective.
"I am writing to you to address the recent discovery of host cell DNA fragments within the Pfizer and Moderna COVID-19 mRNA vaccines," Ladapo noted in his letter to FDA Commissioner Robert Califf and CDC Director Mandy Cohen.
"This raises concerns regarding the presence of nucleic acid contaminants in the approved Pfizer and Moderna COVID-19 mRNA vaccines, particularly in the presence of lipid nanoparticle complexes, and Simian Virus 40 (SV40) promoter/enhancer DNA. Lipid nanoparticles are an efficient vehicle for delivery of the mRNA in the COVID-19 vaccines into human cells, and may therefore be an equally efficient vehicle for delivering contaminant DNA into human cells. The presence of SV40 promoter/enhancer DNA may also pose a unique and heightened risk of DNA integration into host cells," Ladapo wrote.
He also noted that "it is essential to human health to assess the risks of contaminant DNA integration into human DNA."
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But when responding to Ladapo, Marks conveyed the FDA's contention that the vaccines are safe and said that "misinformation and disinformation" causes "vaccine hesitancy that lowers vaccine uptake."
"We would like to make clear that based on a thorough assessment of the entire manufacturing process, FDA is confident in the quality, safety, and effectiveness of the COVID-19 vaccines. The agency's benefitrisk assessment and ongoing safety surveillance demonstrate that the benefits of their use outweigh their risks. Additionally, with over a billion doses of the mRNA vaccines administered, no safety concerns related to residual DNA have been identified," Marks wrote.
"No SV40 proteins are encoded for or are present in the vaccines. On first principle, it is quite implausible that the residual small DNA fragments located in the cytosol could find their way into the nucleus through the nuclear membrane present in intact cells and then be incorporated into chromosomal DNA," Marks wrote. "Additionally, studies have been conducted in animals using the modified mRNA and lipid nanoparticle together that constitute the vaccine, including the minute quantities of residual DNA fragments left over after DNAse treatment during manufacturing, and demonstrate no evidence for genotoxicity from the vaccine. Pharmacovigilance data in hundreds of millions of individuals also indicate no evidence indicative of genotoxicity."
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Natural immunity provides better protection against COVID than vaccines – even against hospitalization, new study finds
People with natural immunity to COVID-19 have better protection against the respiratory disease than those who received mRNA vaccines, according to a new study.
A group of researchers from Estonia took a pool of 329,496 adults between Feb. 26, 2020, and June 25, 2021.
The analysis was based on data from 246,113 individuals who qualified as one of four categories. The scientists categorized the individuals as those with no immunity against COVID, those with natural immunity from previously being infected, those who had vaccine-induced immunity, and those who had both natural immunity and who were vaccinated against SARS-CoV-2.
"Natural immunity conferred substantial protection against COVID-19 hospitalization," the authors of the study wrote. "Our study showed that natural immunity offers stronger and longer-lasting protection against infection, symptoms, and hospitalization compared to vaccine-induced immunity."
The Epoch Times reported, "People who received a vaccine were nearly five times as likely as the naturally immune to test positive for COVID-19 during the Delta era and 1.1 times as likely to test positive for COVID-19 during the Omicron era, researchers in Estonia found."
Individuals who were vaccinated against COVID were seven times as likely to be hospitalized during the Delta variant era, and two times when the Omicron variant was spreading, according to the outlet.
The study declared that hospitalization due to COVID was "extremely rare" for those with hybrid immunity. The researchers discovered that hybrid immunity had "substantially lower rates of reinfection" than those with natural immunity. However, the protection was diminished during the Omicron period.
The Estonian researchers noted, "Studies on the effectiveness of COVID-19 vaccines suggest that protection against SARS-CoV-2 decreases over time, waning considerably after six months."
The authors concluded, "Our findings suggest that the risk of infection (and of developing severe disease) is affected not only by age and comorbidities but also by personal history of immunity-conferring events and by the viral variant responsible for the epidemic. Therefore, personalized risk-based vaccination strategies could be both effective and cost-effective."
The study was published on Nov. 21 in Scientific Reports – a peer-reviewed journal that is part of the Nature Portfolio and covers natural sciences, psychology, medicine, and engineering.
In February, a study was published that declared that natural immunity provides "at least as high, if not higher" levels of protection against COVID-19 as two doses of an mRNA vaccine. The research analyzing 65 studies from 19 different countries was published in The Lancet – one of the oldest and most respected medical journals in the world.
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